Jennie Maris, Author at NIHR

New partnership to take potential treatment for motor neuron disease (MND) into clinical trials

22nd September 2020Jennie MarisAclipse, FIGHTMND, M102, MND, SITraN, University of Sheffield

Researchers from the University of Sheffield’s Institute for Translational Neuroscience (SITraN) have been awarded a $700,000 drug development grant to progress a potential targeted therapy for motor neuron disease (MND) into clinical trials. The grant, awarded by Australian charity FightMND, will support SITraN’s partnership with Aclipse Therapeutics to progress a disease-modifying drug candidate – M102…

New investigational drug shows potential in targeting hereditary cause of motor neuron disease

10th July 2020Jennie MarisALS, motor neuron disease, NEJM, New England Journal of Medicine, SITraN, SOD1, Tofersen

Results from a phase 1-2 study published today (9 July 2020) in the New England Journal of Medicine, have shown the new investigational drug tofersen has the potential to reduce the levels of a toxic cell protein, triggered by a faulty gene called SOD1, which causes the progression of the debilitating motor neuron disease. Read…

Sheffield Bioinformatics Core hit incredible milestone of 1000 COVID-19 genomes sequenced in just over 8 weeks!

15th May 2020Jennie Mariscoronavirus, COVID-19, gene sequencing, genomics UK consortium, nanapore, SARS-CoV-2, Shefbioinfcore, sheffield, Sheffield bioinformatics core

Work to rapidly sequence whole genomes of coronavirus is proving ever successful at the University, with a collaborative team contributing sequences from patients with confirmed cases of coronavirus. As part of their work for the consortium, the team has expanded its capacity to be able to sequence around 120 samples per week; initially over a…

Sheffield scientists leading the fight against coronavirus join national consortium to map the outbreak

25th March 2020Jennie Maris

Our researchers are part of the new UK whole genome sequencing alliance to rapidly map and analyse how coronavirus spreads and behaves. Scientists at the University of Sheffield have joined a new research consortium backed by the UK government to help fight coronavirus £20 million investment will allow scientists and clinicians across the UK to…

Sheffield Hospitals Charity shines a light on their MS Appeal

25th March 2020Jennie Maris

Our NIHR Sheffield BRC Clinical Team Lead, Alex Radford, is backing a major new fundraising appeal by Sheffield Hospitals Charity which could bring new hope to people suffering from Multiple Sclerosis (MS). MS affects more than 100,000 people in the UK and is the most common cause of physical disability in young adults. It…

Whole genomes of coronavirus from UK patients sequenced by Sheffield scientists

19th March 2020Jennie Maris

Scientists at the University of Sheffield in partnership with Sheffield Teaching Hospitals Virology team have successfully sequenced their first two whole genomes of the novel coronavirus (COVID-19) from UK patients The work forms part of a worldwide emergency response to the outbreak, helping coordinate agile responses to new infectious diseases as they spread and mutate…

DHSC issues guidance on the impact of COVID-19 on research funded or supported by NIHR

19th March 2020Jennie Maris

Given the scale of the national and global challenge of COVID-19, clinical and academic health & care professionals currently funded by NIHR who are working on topics other than COVID-19 have been asked to prioritise frontline care. Working with partners across the health and care system, NIHR enables and delivers world-class research that transforms people’s…

Posts by Jennie Maris