Jennie Maris, Author at NIHR

Working with industry to deliver the next generation of medicine

26th April 2021Jennie MarisIndustry, InnovatingWithIndustry, LeedsBRC, ManchesterBRC, NewcastleBRC, NHSA

World-leading translational research centres across the North have come together to showcase their ground-breaking research with industry partners to deliver the next generation of medicine. The four Northern NIHR Biomedical Research Centres (BRCs) in Leeds, Manchester, Newcastle and Sheffield have published ‘NIHR Northern BRC Collaborative: Innovating with Industry’ supported by the Northern Health Science Alliance (NHSA). The BRCs in the North are…

The Sheffield PET-MRI Facility is the UKs 8th and Yorkshires only PET-MRI Facility

14th April 2021Jennie Maris3T, GE, Imaging, MRI, PET, PET-MRi, Sheffield Scanner

The Sheffield PET-MRI scanner is set in a purpose built state-of-the-art facility that is attached to the existing University of Sheffield MRI unit at the Royal Hallamshire Hospital. It will provide unprecedented views of inside the human body by combining the power of both MRI and PET images in a single scan. It will help…

New gene therapy innovation centre to advance scientific discoveries into life-changing treatments

18th March 2021Jennie Marisadvanced therapy, Gene therapy, genetics research, GTIMC, innovation, novel treatments, Rare disease, University of Sheffield

A pioneering gene therapy innovation centre at the University of Sheffield is set to advance scientific discoveries into promising treatment options for millions of patients with life-threatening diseases. The Gene Therapy Innovation and Manufacturing Centre (GTIMC), led by Professor Mimoun Azzouz, is one of three pioneering hubs announced today (18 March 2021) in a new…

Training and Career Development Opportunities 2021

4th February 2021Jennie Maris

Obesity may exacerbate the effects of Alzheimer’s disease, new study shows

4th February 2021Jennie Marisalzheimers, cognitive impairment, dementia, grey matter, neuroimaging, obesity

New research has found being overweight is an additional burden on brain health and it may exacerbate Alzheimer’s disease. The pioneering multimodal neuroimaging study revealed obesity may contribute toward neural tissue vulnerability, whilst maintaining a healthy weight in mild Alzheimer’s disease dementia could help to preserve brain structure. The findings, published in The Journal of…

New partnership to take potential treatment for motor neuron disease (MND) into clinical trials

22nd September 2020Jennie MarisAclipse, FIGHTMND, M102, MND, SITraN, University of Sheffield

Researchers from the University of Sheffield’s Institute for Translational Neuroscience (SITraN) have been awarded a $700,000 drug development grant to progress a potential targeted therapy for motor neuron disease (MND) into clinical trials. The grant, awarded by Australian charity FightMND, will support SITraN’s partnership with Aclipse Therapeutics to progress a disease-modifying drug candidate – M102…

New investigational drug shows potential in targeting hereditary cause of motor neuron disease

10th July 2020Jennie MarisALS, motor neuron disease, NEJM, New England Journal of Medicine, SITraN, SOD1, Tofersen

Results from a phase 1-2 study published today (9 July 2020) in the New England Journal of Medicine, have shown the new investigational drug tofersen has the potential to reduce the levels of a toxic cell protein, triggered by a faulty gene called SOD1, which causes the progression of the debilitating motor neuron disease. Read…

Sheffield Bioinformatics Core hit incredible milestone of 1000 COVID-19 genomes sequenced in just over 8 weeks!

15th May 2020Jennie Mariscoronavirus, COVID-19, gene sequencing, genomics UK consortium, nanapore, SARS-CoV-2, Shefbioinfcore, sheffield, Sheffield bioinformatics core

Work to rapidly sequence whole genomes of coronavirus is proving ever successful at the University, with a collaborative team contributing sequences from patients with confirmed cases of coronavirus. As part of their work for the consortium, the team has expanded its capacity to be able to sequence around 120 samples per week; initially over a…

Sheffield scientists leading the fight against coronavirus join national consortium to map the outbreak

25th March 2020Jennie Maris

Our researchers are part of the new UK whole genome sequencing alliance to rapidly map and analyse how coronavirus spreads and behaves. Scientists at the University of Sheffield have joined a new research consortium backed by the UK government to help fight coronavirus £20 million investment will allow scientists and clinicians across the UK to…

Sheffield Hospitals Charity shines a light on their MS Appeal

25th March 2020Jennie Maris

Our NIHR Sheffield BRC Clinical Team Lead, Alex Radford, is backing a major new fundraising appeal by Sheffield Hospitals Charity which could bring new hope to people suffering from Multiple Sclerosis (MS). MS affects more than 100,000 people in the UK and is the most common cause of physical disability in young adults. It…

Posts by Jennie Maris